ISSCR News
Two Early Career Editors Join the Stem Cell Reports Editorial Board, Expand Scientific Expertise and Global Reach
Stem Cell Reports, the peer-reviewed, open-access journal of the International Society for Stem Cell Research (ISSCR), today announced the appointment of two new Early Career Editors – Bo Shen, Ph.D., Principal Investigator at the National Institute of Biological Sciences, Beijing (NIBS) and Assistant Professor at Tsinghua University, China; and Luca Peruzzotti-Jametti, M.D., Ph.D., Clinical Principal Research Associate at the Department of Clinical Neurosciences, and Group Leader at the MS Society Cambridge Centre for Myelin Repair (CCMR) at the University of Cambridge; and Honorary Senior Lecturer, Department of Metabolism, Digestion and Reproduction, Imperial College London, UK.
New Study Shows Gut Microbiota Directly Regulates Intestinal Stem Cell Aging
A new study led by Hartmut Geiger at the University of Ulm, Germany, and Yi Zheng and Kodandaramireddy Nalapareddy, Cincinnati Children's Hospital Medical Center (CCHMC), USA reveals that age-related changes in the gut microbiota directly impair intestinal stem cell (ISC) function and that restoring a youthful microbial environment can reverse this decline. The results were published today in Stem Cell Reports.
ISSCR Develops Roadmap to Accelerate Pluripotent Stem Cell-Derived Therapies to Patients
The International Society for Stem Cell Research (ISSCR) today announced the upcoming release of “Charting the Translational Pathway: ISSCR Best Practices for the Development of Pluripotent Stem Cell (PSC)-Derived Therapies,” a new paper highlighting some of the most critical aspects of the ISSCR’s breakthrough interactive resource designed to transform how PSC-derived therapies are developed, evaluated, and advanced toward clinical and commercial success. The paper was published today in Stem Cell Reports.
New Podcast Episode. Tuning the X.
Epigenetic regulation of gene expression is an important mechanism in development and disease. N6-methyladenosine (m6A) is one of the most prevalent epigenetic modifications for RNA and has been shown to play critical roles in processes such as embryo development, cancer, and stress responses. Our guests today investigate how m6A regulates X chromosome dosage compensation to ensure proper balance of gene expression from X chromosomes between sexes. X-chromosome dosage compensation is accomplished through two complementary mechanisms. First, X-chromosome inactivation (XCI) silences one of the two X chromosomes in female cells. Second, the remaining active X chromosome is transcriptionally upregulated so that its gene expression levels are balanced with those of the autosomes, a process known as X-to-autosome (X-to-A) compensation. The authors dissect the distinct contributions of m6A RNA methylation to XCI versus X-to-A compensation across multiple embryonic lineages, providing deeper insights into the epigenetic regulation of early development.
Stem Cell Reports Seeks Early Career Editors to Join the Editorial Board
Stem Cell Reports, the peer-reviewed, open-access journal of the International Society for Stem Cell Research (ISSCR), today announced a call for applications to serve on its editorial team, a prestigious opportunity for outstanding, early-career scientists to help shape the future of stem cell publishing. The deadline to apply is 13 March 2026.
Selected members will serve up to a three-year term beginning 1 September 2026, joining a cohort of distinguished early career researchers who will play an active role in the journal’s scientific vision and community engagement. The program is designed to provide hands-on editorial experience, mentorship, and professional visibility within the global stem cell research community.
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